Certificate of Analysis
Purity
≥98.0%
Method
HPLC / MS
Testing
Third-Party
COA Status
Available
MOTS-c
A research compound studied in laboratory models involving mitochondrial signaling, cellular stress response, and biological pathway investigation.
Select Size / Specification
Selected: 10mg x 10vials
Choose Pack Size
Quantity
Research Use Only — All products are intended strictly for laboratory research purposes and are not for human consumption. Not intended to diagnose, treat, cure, or prevent any disease.
Pricing & Specifications
| Specification | Strength | Pack | Total Qty | 1 Vial | 3 Vial Bundle | 10 Vial Kit | Kit Savings |
|---|---|---|---|---|---|---|---|
| 10mg x 10vials | 10 MG | 10 | 100 MG | $95.00 | $270.75 | $712.5025% off | $237.50 |
| 40mg x 10vials | 40 MG | 10 | 400 MG | $315.00 | $897.75 | $2,362.5025% off | $787.50 |
About MOTS-c
MOTS-c (Mitochondrial Open Reading Frame of the 12S rRNA, type c) is a 16-amino acid peptide encoded by a short open reading frame (sORF) within the mitochondrial 12S ribosomal RNA gene. Discovered in 2015, MOTS-c is translated in the mitochondrial matrix using the standard mitochondrial genetic code and subsequently exported to the cytoplasm and nucleus. It represents one of the first described mitochondrial-derived peptides (MDPs) — a class of small regulatory peptides encoded entirely within the mitochondrial genome.
Research interest in MOTS-c has focused on its translocation from the cytoplasm to the nucleus in response to metabolic stress, where it has been shown to interact with nuclear transcription factor binding sites including ARE (antioxidant response elements). In vitro studies have characterized its effects on AMPK pathway activation, glucose metabolism regulation in skeletal muscle cell models, and oxidative stress response pathway modulation. MOTS-c is considered an important research tool for studying mitochondrial-nuclear communication mechanisms. For laboratory research use only.
Peptide / Compound Information
| Property | Value |
|---|---|
| Peptide Sequence | Met-Arg-Trp-Gln-Glu-Met-Gly-Tyr-Ile-Phe-Tyr-Pro-Arg-Lys-Leu-Arg |
| Molecular Formula | C99H173N35O27 |
| Molecular Weight | 2,174.7 g/mol |
| CAS Number | 1627580-50-0 |
| Synonyms | Mitochondrial ORF of the 12S rRNA type-c, MOTS-c peptide, Humanin-related peptide |
Lyophilized Research Peptides
This product is supplied in lyophilized (freeze-dried) form — a process that extends shelf life and preserves peptide purity and structural integrity during storage. No fillers, excipients, or preservatives are used in the lyophilization process. The lyophilized powder should be reconstituted with an appropriate research-grade solvent in a controlled laboratory environment prior to use in in vitro or preclinical assay systems.
99%+
PURITY
Third Party Tested
Independently verified by ISO-accredited laboratories. Batch-specific COAs available on request.
GMP
CERT.
GMP Manufacturing Standards
Synthesized in registered facilities following Good Manufacturing Practices with full chain-of-custody documentation.
FAST
SHIP
Best in Class Fulfillment
Same-day fulfillment on qualifying orders. Secure cold-chain packaging. Domestic and international research shipping.
ZERO
FILLERS
Zero Fillers or Additives
Pure active compounds only. Lyophilized without fillers or preservatives. Composition independently verified.
Scientific Content Review
All technical product descriptions, molecular data, and research context on this page have been prepared with reference to published scientific literature and PubChem compound databases. Content is intended for informational purposes in a research catalog context and does not constitute medical advice or claim therapeutic efficacy.
MOTS-c is a research compound available for controlled laboratory investigation and scientific study. This product is intended strictly for in vitro research, preclinical investigation, and analytical characterization by qualified researchers. Not for human consumption.
Category
Mitochondrial / Longevity
Purity
≥98.0%
Available Sizes
10MG, 40MG
COA
Available
Overview
MOTS-c is a research compound available for controlled laboratory investigation and scientific study. This product is intended strictly for in vitro research, preclinical investigation, and analytical characterization by qualified researchers. Not for human consumption.
Category
Mitochondrial / Longevity
Purity
≥98.0%
Available Sizes
10MG, 40MG
COA
Available
Research Interest
Research interest includes mitochondrial bioenergetics studies, telomere biology modeling, cellular senescence investigations, and antioxidant pathway analysis in controlled laboratory settings. Scientific literature examines this compound in the context of aging biology models and cellular energy pathway characterization.
Scientific Literature Note
Research interest data is provided for scientific reference purposes only, based on published preclinical or in vitro literature. No claims regarding human therapeutic outcomes are made or implied.
Specifications
| Specification | Unit Strength | Unit | Pack Size | Total Active Qty |
|---|---|---|---|---|
| 10mg x 10vials | 10 | MG | 10 vials | 100 MG |
| 40mg x 10vials | 40 | MG | 10 vials | 400 MG |
Quality / COA
Each batch is prepared to research-grade analytical standards. HPLC purity verification and mass spectrometry confirmation are performed for every lot. A batch-specific Certificate of Analysis (COA) is available identifying lot number, purity percentage, testing methodology, and third-party laboratory credentials.
COA Summary
Purity
≥98.0%
Testing Method
HPLC / ESI-MS
Lab Type
ISO-Accredited
Availability
On Request
HPLC purity verification
Mass spectrometry confirmation
Independent third-party lab
Lot-specific documentation
Storage
Store lyophilized compound at −20°C or below. Protect from light and moisture. Refer to the Certificate of Analysis for complete handling and storage specifications. Follow all applicable laboratory safety protocols and institutional regulations.
Temperature
−20°C or below
Long-term storage
Light
Protected
Avoid UV exposure
Form
Lyophilized
Until lab use
Disclaimer
Research Use Only — All products are intended strictly for laboratory research purposes and are not for human consumption. Not intended to diagnose, treat, cure, or prevent any disease.
For laboratory research use only. Not for human consumption. This product is not intended to diagnose, treat, cure, or prevent any disease. Sold exclusively for in vitro and preclinical research applications by qualified researchers.
Products are sold exclusively for in vitro research, preclinical investigation, and laboratory study. Purchasers are responsible for compliance with all applicable laws and regulations in their jurisdiction.
Mitochondrial / Longevity
Related Research Compounds
Longevity Research
NAD
A coenzyme compound studied in laboratory research related to cellular energy metabolism, NAD+ biosynthesis pathway analysis, and mitochondrial bioenergetics investigation.
From $75.00
Longevity Research
Epithalon
A synthetic tetrapeptide bioregulator studied in laboratory models related to telomere biology, cellular senescence research, and pineal gland peptide pathway analysis.
From $16.00
Longevity Research
SS-31
A mitochondria-targeted peptide studied in laboratory research involving mitochondrial membrane potential modeling, reactive oxygen species analysis, and cellular energy pathway investigation.
From $105.00
Longevity Research
Thymalin
A research compound studied in laboratory models involving mitochondrial signaling, cellular stress response, and biological pathway investigation.
From $60.00