Certificate of Analysis
Purity
≥98.0%
Method
HPLC / MS
Testing
Third-Party
COA Status
Available
MT-1
A research compound studied in laboratory models involving melanocortin receptor pathway analysis and pigmentation biology research.
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Quantity
Research Use Only — All products are intended strictly for laboratory research purposes and are not for human consumption. Not intended to diagnose, treat, cure, or prevent any disease.
About MT-1
MT-1 (afamelanotide; [Nle4,D-Phe7]-α-MSH) is a potent synthetic 13-amino acid analog of α-melanocyte-stimulating hormone (α-MSH) incorporating two key modifications: norleucine (Nle) substitution at position 4 in place of methionine (increasing oxidative stability) and a D-Phe substitution at position 7 (the critical pharmacophore residue), which dramatically increases receptor binding affinity and metabolic stability relative to native α-MSH. The sequence retains the core His-Phe-Arg-Trp melanocortin pharmacophore essential for MC receptor activation.
MT-1 exhibits high-affinity agonist activity at melanocortin receptor subtypes MC1R through MC5R in binding assay systems, with particular potency at MC1R — the primary receptor expressed on melanocytes. Research investigations have characterized its receptor activation profiles, downstream cAMP accumulation kinetics, G-protein coupling selectivity, and effects on melanin synthesis pathway upregulation in cultured melanocyte models. The compound is used as a potent reference standard in melanocortin receptor pharmacology studies and is provided for qualified laboratory research use only.
Peptide / Compound Information
| Property | Value |
|---|---|
| Peptide Sequence | Ac-Ser-Tyr-Ser-Nle-Glu-His-D-Phe-Arg-Trp-Gly-Lys-Pro-Val-NH₂ |
| Molecular Formula | C78H111N21O20S2 |
| Molecular Weight | 1,646.9 g/mol |
| CAS Number | 75921-69-6 |
| Synonyms | Afamelanotide, [Nle4,D-Phe7]-α-MSH, Scenesse (reference), NDP-α-MSH |
Lyophilized Research Peptides
This product is supplied in lyophilized (freeze-dried) form — a process that extends shelf life and preserves peptide purity and structural integrity during storage. No fillers, excipients, or preservatives are used in the lyophilization process. The lyophilized powder should be reconstituted with an appropriate research-grade solvent in a controlled laboratory environment prior to use in in vitro or preclinical assay systems.
99%+
PURITY
Third Party Tested
Independently verified by ISO-accredited laboratories. Batch-specific COAs available on request.
GMP
CERT.
GMP Manufacturing Standards
Synthesized in registered facilities following Good Manufacturing Practices with full chain-of-custody documentation.
FAST
SHIP
Best in Class Fulfillment
Same-day fulfillment on qualifying orders. Secure cold-chain packaging. Domestic and international research shipping.
ZERO
FILLERS
Zero Fillers or Additives
Pure active compounds only. Lyophilized without fillers or preservatives. Composition independently verified.
Scientific Content Review
All technical product descriptions, molecular data, and research context on this page have been prepared with reference to published scientific literature and PubChem compound databases. Content is intended for informational purposes in a research catalog context and does not constitute medical advice or claim therapeutic efficacy.
MT-1 is a research compound available for controlled laboratory investigation and scientific study. This product is intended strictly for in vitro research, preclinical investigation, and analytical characterization by qualified researchers. Not for human consumption.
Category
Pigmentation / Tanning
Purity
≥98.0%
Available Sizes
5MG
COA
Available
Overview
MT-1 is a research compound available for controlled laboratory investigation and scientific study. This product is intended strictly for in vitro research, preclinical investigation, and analytical characterization by qualified researchers. Not for human consumption.
Category
Pigmentation / Tanning
Purity
≥98.0%
Available Sizes
5MG
COA
Available
Research Interest
Research interest includes melanocortin receptor binding studies, pigmentation pathway analysis, and peptide characterization in controlled in vitro research settings. Scientific literature references this compound in the context of MC1R pathway analysis and pigmentation biology modeling.
Scientific Literature Note
Research interest data is provided for scientific reference purposes only, based on published preclinical or in vitro literature. No claims regarding human therapeutic outcomes are made or implied.
Specifications
| Specification | Unit Strength | Unit | Pack Size | Total Active Qty |
|---|---|---|---|---|
| 5mg x 10vials | 5 | MG | 10 vials | 50 MG |
Quality / COA
Each batch is prepared to research-grade analytical standards. HPLC purity verification and mass spectrometry confirmation are performed for every lot. A batch-specific Certificate of Analysis (COA) is available identifying lot number, purity percentage, testing methodology, and third-party laboratory credentials.
COA Summary
Purity
≥98.0%
Testing Method
HPLC / ESI-MS
Lab Type
ISO-Accredited
Availability
On Request
HPLC purity verification
Mass spectrometry confirmation
Independent third-party lab
Lot-specific documentation
Storage
Store lyophilized compound at −20°C or below. Protect from light and moisture. Refer to the Certificate of Analysis for complete handling and storage specifications. Follow all applicable laboratory safety protocols and institutional regulations.
Temperature
−20°C or below
Long-term storage
Light
Protected
Avoid UV exposure
Form
Lyophilized
Until lab use
Disclaimer
Research Use Only — All products are intended strictly for laboratory research purposes and are not for human consumption. Not intended to diagnose, treat, cure, or prevent any disease.
For laboratory research use only. Not for human consumption. This product is not intended to diagnose, treat, cure, or prevent any disease. Sold exclusively for in vitro and preclinical research applications by qualified researchers.
Products are sold exclusively for in vitro research, preclinical investigation, and laboratory study. Purchasers are responsible for compliance with all applicable laws and regulations in their jurisdiction.
