Certificate of Analysis
Purity
≥98.0%
Method
HPLC / MS
Testing
Third-Party
COA Status
Available
IGF-DES
A research compound studied in controlled laboratory settings for scientific investigation and analytical characterization.
Choose Pack Size
Quantity
Research Use Only — All products are intended strictly for laboratory research purposes and are not for human consumption. Not intended to diagnose, treat, cure, or prevent any disease.
About IGF-DES
IGF-1 DES (des(1-3)IGF-1) is a naturally occurring truncated form of insulin-like growth factor-1 (IGF-1), in which the first three N-terminal amino acids (Gly-Pro-Glu) are removed. This truncation eliminates a significant portion of the binding domain for IGF binding proteins (IGFBPs) — particularly IGFBP-3 — while preserving full agonist activity at the IGF-1 receptor (IGF-1R). As a result, DES-IGF-1 exhibits markedly reduced affinity for circulating IGFBPs in vitro (approximately 50-fold lower than full-length IGF-1), potentially increasing the free, biologically active fraction in experimental models.
Research interest in IGF-1 DES centers on its use as a tool to study IGF-1R signaling independently of IGFBP-mediated buffering, enabling investigation of receptor activation pharmacology without confounding IGFBP competition. Research applications include IGF-1R binding kinetics determination, downstream IRS-1/PI3K/Akt and Ras/ERK1/2 signaling pathway characterization in cell models, and comparative potency studies between full-length IGF-1 and IGFBP-resistant truncated variants. For qualified laboratory research use only.
Peptide / Compound Information
| Property | Value |
|---|---|
| Peptide Sequence | GPE-IGF-1: des(1-3) N-terminal truncated IGF-1 (68 AA from position 4 onward of full-length IGF-1) |
| Molecular Formula | C319H503N95O94S6 |
| Molecular Weight | 7,371.4 g/mol |
| CAS Number | 112603-37-9 |
| Synonyms | IGF-1 DES(1-3), Truncated IGF-1, des(1-3)IGF-1, IGF-DES |
Lyophilized Research Peptides
This product is supplied in lyophilized (freeze-dried) form — a process that extends shelf life and preserves peptide purity and structural integrity during storage. No fillers, excipients, or preservatives are used in the lyophilization process. The lyophilized powder should be reconstituted with an appropriate research-grade solvent in a controlled laboratory environment prior to use in in vitro or preclinical assay systems.
99%+
PURITY
Third Party Tested
Independently verified by ISO-accredited laboratories. Batch-specific COAs available on request.
GMP
CERT.
GMP Manufacturing Standards
Synthesized in registered facilities following Good Manufacturing Practices with full chain-of-custody documentation.
FAST
SHIP
Best in Class Fulfillment
Same-day fulfillment on qualifying orders. Secure cold-chain packaging. Domestic and international research shipping.
ZERO
FILLERS
Zero Fillers or Additives
Pure active compounds only. Lyophilized without fillers or preservatives. Composition independently verified.
Scientific Content Review
All technical product descriptions, molecular data, and research context on this page have been prepared with reference to published scientific literature and PubChem compound databases. Content is intended for informational purposes in a research catalog context and does not constitute medical advice or claim therapeutic efficacy.
IGF-DES is a research compound available for controlled laboratory investigation and scientific study. This product is intended strictly for in vitro research, preclinical investigation, and analytical characterization by qualified researchers. Not for human consumption.
Category
Other
Purity
≥98.0%
Available Sizes
2MG
COA
Available
Overview
IGF-DES is a research compound available for controlled laboratory investigation and scientific study. This product is intended strictly for in vitro research, preclinical investigation, and analytical characterization by qualified researchers. Not for human consumption.
Category
Other
Purity
≥98.0%
Available Sizes
2MG
COA
Available
Research Interest
Research interest encompasses pathway analysis, receptor interaction studies, and compound behavior investigations in controlled laboratory and preclinical research settings. Areas of study include peptide stability, cellular signaling dynamics, and analytical characterization.
Scientific Literature Note
Research interest data is provided for scientific reference purposes only, based on published preclinical or in vitro literature. No claims regarding human therapeutic outcomes are made or implied.
Specifications
| Specification | Unit Strength | Unit | Pack Size | Total Active Qty |
|---|---|---|---|---|
| 2 mg x 10vials | 2 | MG | 10 vials | 20 MG |
Quality / COA
Each batch is prepared to research-grade analytical standards. HPLC purity verification and mass spectrometry confirmation are performed for every lot. A batch-specific Certificate of Analysis (COA) is available identifying lot number, purity percentage, testing methodology, and third-party laboratory credentials.
COA Summary
Purity
≥98.0%
Testing Method
HPLC / ESI-MS
Lab Type
ISO-Accredited
Availability
On Request
HPLC purity verification
Mass spectrometry confirmation
Independent third-party lab
Lot-specific documentation
Storage
Store lyophilized compound at −20°C or below. Protect from light and moisture. Refer to the Certificate of Analysis for complete handling and storage specifications. Follow all applicable laboratory safety protocols and institutional regulations.
Temperature
−20°C or below
Long-term storage
Light
Protected
Avoid UV exposure
Form
Lyophilized
Until lab use
Disclaimer
Research Use Only — All products are intended strictly for laboratory research purposes and are not for human consumption. Not intended to diagnose, treat, cure, or prevent any disease.
For laboratory research use only. Not for human consumption. This product is not intended to diagnose, treat, cure, or prevent any disease. Sold exclusively for in vitro and preclinical research applications by qualified researchers.
Products are sold exclusively for in vitro research, preclinical investigation, and laboratory study. Purchasers are responsible for compliance with all applicable laws and regulations in their jurisdiction.
Other
Related Research Compounds
Research Use Only
Glutathione
A tripeptide antioxidant studied in laboratory research involving oxidative stress pathway modeling, cellular redox balance investigations, and antioxidant cascade characterization.
From $53.00
Research Use Only
TB500(Thymosin B4 Acetate)
A research compound studied in controlled laboratory settings for scientific investigation and analytical characterization.
From $40.00
Research Use Only
PT-141
A melanocortin research peptide studied in laboratory models involving melanocortin receptor binding analysis and neuropeptide pathway characterization.
From $70.00
Lab Supply
BAC Water
A laboratory support item used in research workflows for peptide reconstitution and product handling processes.
From $24.99