Certificate of Analysis
Purity
≥98.0%
Method
HPLC / MS
Testing
Third-Party
COA Status
Available
LL37
A research compound studied in controlled laboratory settings for scientific investigation and analytical characterization.
Choose Pack Size
Quantity
Research Use Only — All products are intended strictly for laboratory research purposes and are not for human consumption. Not intended to diagnose, treat, cure, or prevent any disease.
About LL37
LL-37 is the C-terminal 37-amino acid cathelicidin peptide fragment cleaved from the human cathelicidin precursor protein hCAP-18 by serine protease activity. The peptide adopts an amphipathic α-helical secondary structure in membrane-mimicking environments, with cationic residues along one helix face and hydrophobic residues along the other — a configuration typical of membrane-active antimicrobial peptides. LL-37 is primarily expressed in neutrophils, macrophages, mast cells, and epithelial cells, and represents the sole cathelicidin in the human proteome.
Research investigations of LL-37 encompass its membrane-disruption mechanisms in model lipid bilayer systems (using CD spectroscopy and fluorescence assays), toll-like receptor (TLR) signaling modulation studies, chemotactic activity at FPRL1/FPR2 receptors in leukocyte migration assays, and investigation of its nuclear entry and intracellular gene regulatory functions in epithelial cell models. The compound is also studied for its effects on angiogenesis via VEGF receptor transactivation and as a modulator of inflammatory signaling in controlled cell culture settings.
Peptide / Compound Information
| Property | Value |
|---|---|
| Peptide Sequence | Leu-Leu-Gly-Asp-Phe-Phe-Arg-Lys-Ser-Lys-Glu-Lys-Ile-Gly-Lys-Glu-Phe-Lys-Arg-Ile-Val-Gln-Arg-Ile-Lys-Asp-Phe-Leu-Arg-Asn-Leu-Val-Pro-Arg-Thr-Glu-Ser |
| Molecular Formula | C205H340N60O53S2 |
| Molecular Weight | 4,493.4 g/mol |
| CAS Number | 154947-66-7 |
| Synonyms | Cathelicidin LL-37, hCAP18(134-170), CAMP (Cathelicidin Antimicrobial Peptide) |
Lyophilized Research Peptides
This product is supplied in lyophilized (freeze-dried) form — a process that extends shelf life and preserves peptide purity and structural integrity during storage. No fillers, excipients, or preservatives are used in the lyophilization process. The lyophilized powder should be reconstituted with an appropriate research-grade solvent in a controlled laboratory environment prior to use in in vitro or preclinical assay systems.
99%+
PURITY
Third Party Tested
Independently verified by ISO-accredited laboratories. Batch-specific COAs available on request.
GMP
CERT.
GMP Manufacturing Standards
Synthesized in registered facilities following Good Manufacturing Practices with full chain-of-custody documentation.
FAST
SHIP
Best in Class Fulfillment
Same-day fulfillment on qualifying orders. Secure cold-chain packaging. Domestic and international research shipping.
ZERO
FILLERS
Zero Fillers or Additives
Pure active compounds only. Lyophilized without fillers or preservatives. Composition independently verified.
Scientific Content Review
All technical product descriptions, molecular data, and research context on this page have been prepared with reference to published scientific literature and PubChem compound databases. Content is intended for informational purposes in a research catalog context and does not constitute medical advice or claim therapeutic efficacy.
LL37 is a research compound available for controlled laboratory investigation and scientific study. This product is intended strictly for in vitro research, preclinical investigation, and analytical characterization by qualified researchers. Not for human consumption.
Category
Other
Purity
≥98.0%
Available Sizes
5MG
COA
Available
Overview
LL37 is a research compound available for controlled laboratory investigation and scientific study. This product is intended strictly for in vitro research, preclinical investigation, and analytical characterization by qualified researchers. Not for human consumption.
Category
Other
Purity
≥98.0%
Available Sizes
5MG
COA
Available
Research Interest
Research interest encompasses pathway analysis, receptor interaction studies, and compound behavior investigations in controlled laboratory and preclinical research settings. Areas of study include peptide stability, cellular signaling dynamics, and analytical characterization.
Scientific Literature Note
Research interest data is provided for scientific reference purposes only, based on published preclinical or in vitro literature. No claims regarding human therapeutic outcomes are made or implied.
Specifications
| Specification | Unit Strength | Unit | Pack Size | Total Active Qty |
|---|---|---|---|---|
| 5mg x 10vials | 5 | MG | 10 vials | 50 MG |
Quality / COA
Each batch is prepared to research-grade analytical standards. HPLC purity verification and mass spectrometry confirmation are performed for every lot. A batch-specific Certificate of Analysis (COA) is available identifying lot number, purity percentage, testing methodology, and third-party laboratory credentials.
COA Summary
Purity
≥98.0%
Testing Method
HPLC / ESI-MS
Lab Type
ISO-Accredited
Availability
On Request
HPLC purity verification
Mass spectrometry confirmation
Independent third-party lab
Lot-specific documentation
Storage
Store lyophilized compound at −20°C or below. Protect from light and moisture. Refer to the Certificate of Analysis for complete handling and storage specifications. Follow all applicable laboratory safety protocols and institutional regulations.
Temperature
−20°C or below
Long-term storage
Light
Protected
Avoid UV exposure
Form
Lyophilized
Until lab use
Disclaimer
Research Use Only — All products are intended strictly for laboratory research purposes and are not for human consumption. Not intended to diagnose, treat, cure, or prevent any disease.
For laboratory research use only. Not for human consumption. This product is not intended to diagnose, treat, cure, or prevent any disease. Sold exclusively for in vitro and preclinical research applications by qualified researchers.
Products are sold exclusively for in vitro research, preclinical investigation, and laboratory study. Purchasers are responsible for compliance with all applicable laws and regulations in their jurisdiction.
Other
Related Research Compounds
Research Use Only
Glutathione
A tripeptide antioxidant studied in laboratory research involving oxidative stress pathway modeling, cellular redox balance investigations, and antioxidant cascade characterization.
From $53.00
Research Use Only
TB500(Thymosin B4 Acetate)
A research compound studied in controlled laboratory settings for scientific investigation and analytical characterization.
From $40.00
Research Use Only
PT-141
A melanocortin research peptide studied in laboratory models involving melanocortin receptor binding analysis and neuropeptide pathway characterization.
From $70.00
Lab Supply
BAC Water
A laboratory support item used in research workflows for peptide reconstitution and product handling processes.
From $24.99